Serological diagnosis in gonorrhoea.

A comparison of serological tests for the diagnosis of gonorrhoea.

Gonorrhoea in the chimpanzee. Serological testing.

This laboratory, with a special interest in the serodiagnosis of gonorrhoea, has become active in all aspects of serological testing of animal models as well as humans. Lucas, Chandler, Martin, and Schmale (1971) established the chimpanzee as the first animal model for Neisseria gonorrhoeae. They infected four male chimpanzees with human urethral exudates containing N. gonorrhoeae. Brown, Lucas...

Diagnosis of gonorrhoea in women.

250 consecutive female contacts of men with gonorrhoea were examined in Lydia Department of Genito-urinary Medicine, St Thomas' Hospital, London, and 165 (66 per cent.) were found to be positive for gonorrhoea. Over 99 per cent. of the positive results were found by the first two sets of genital investigations. These results are compared with earlier and more recent results from our own and oth...

Microbiological diagnosis of gonorrhoea.

Gonorrhoea is caused by Neisseria gonorrhoeae. This is a delicate and fastidious organism which dies rapidly if exposed to desiccating or oxidising conditions and requires a moist carbon dioxide enriched atmosphere and a nutrient medium if it is to be cultured successfully. For these reasons diagnosis by culture was regarded as difficult and uncertain, but many decades ago the problems were ove...

Serological diagnosis of gonorrhoea by an enzyme-linked immunosorbent assay (Elisa).

IgG antibody to an outer membrane protein extracted from Neisseria gonorrhoeae was measured in patients with gonorrhoea. The level in such patients was significantly higher than in normal controls or in patients with other conditions who were attending the clinic for sexually transmitted diseases. Significantly higher antibody levels were detectable in half the patients within a few days of inf...